A Look at Corneal Endothelial Cells 6 to 7 Years After Surgery in PES Patients
To assess the condition of the corneal endothelium an extended period after cataract surgery in eyes with and without pseudoexfoliation syndrome (PES), 46 patients with PES who underwent cataract surgery in the Eye Department at Oslo University Hospital in 2001 and 2002 were enrolled and compared to 101 matched controls without PES who had surgery in the same period. They were re-examined six to seven years following surgery with measurements of corneal endothelial cell density (ECD), pleomorphism, polymegathism, and corneal thickness taken.
It was reported that mean ECD was 2,024 cells/mm² ± 371 cells/mm² in eyes with PES and 2,144 cells/mm² ± 365 cells/mm² in eyes without PES. The difference was not statistically significant and no significant difference in polymegathism and pleomorphism was noted. It was also observed that mean corneal thickness was 543 µm and 547 µm in eyes with and without PES, respectively (not statistically significant). Furthermore, the presence of glaucoma in pseudoexfoliative eyes was not associated with endothelial cell changes.
Six to seven years following cataract surgery, no statistically significant differences were established in ECD, pleomorphism, polymegathism, and corneal thickness in eyes with and without PES. Additionally, no clinical signs of corneal decompensation were noted among the participants.